Publications 2020
1. Nijen Twilhaar MK, Czentner Colomo L, Grabowska J, van Kooyk Y, Storm G, den Haan JMM. Optimization of Liposomes for Antigen Targeting to Splenic CD169+ Macrophages. 2020. Poster session presented at NVVI, Netherlands. https://doi.org/10.3390/pharmaceutics12121138
2. Baardman J, Verberk SGS, van der Velden S, Gijbels MJJ, van Roomen CPPA, Sluimer JC et al. Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques. Nature Communications. 2020 Dec 8;11(1). 6296. https://doi.org/10.1038/s41467-020-20141-z
3. Schetters STT, Li RJE, Kruijssen LJW, Engels S, Ambrosini M, Garcia-Vallejo JJ et al. Adaptable antigen matrix platforms for peptide vaccination strategies and T cell-mediated anti-tumor immunity. Biomaterials. 2020 Dec 1;262. 120342. https://doi.org/10.1016/j.biomaterials.2020.120342
4. Brulois K, Rajaraman A, Szade A, Nordling S, Bogoslowski A, Dermadi D et al. A molecular map of murine lymph node blood vascular endothelium at single cell resolution. Nature Communications. 2020 Dec 1;11(1). 3798. https://doi.org/10.1038/s41467-020-17291-5, https://doi.org/10.1038/s41467-020-17291-5
5. Chiodo F. Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus. Nature Communications. 2020 Dec 1;11(1). 4142. https://doi.org/10.1038/s41467-020-17992-x
6. Kes MMG, van den Bossche J, Griffioen AW, Huijbers EJM. Oncometabolites lactate and succinate drive pro-angiogenic macrophage response in tumors. Biochimica et Biophysica Acta - Reviews on Cancer. 2020 Dec 1;1874(2). 188427. https://doi.org/10.1016/j.bbcan.2020.188427
7. Beaino W, Janssen B, Kooijman E, Vos R, Schuit RC, O’Brien-Brown J et al. PET imaging of P2X7R in the experimental autoimmune encephalomyelitis model of multiple sclerosis using [11C]SMW139. Journal of Neuroinflammation. 2020 Dec 1;17(1). 300. https://doi.org/10.1186/s12974-020-01962-7
8. Garcia-Vello P, Speciale I, Chiodo F, Molinaro A, De Castro C. Carbohydrate-based adjuvants. Drug Discovery Today: Technologies. 2020 Dec;35-36:57-68. https://doi.org/10.1016/j.ddtec.2020.09.005
9. Crivelli SM, van Kruining D, Luo Q, Stevens JAA, Giovagnoni C, Paulus A et al. Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe. Scientific Reports. 2020 Dec;10(1). 19354. https://doi.org/10.1038/s41598-020-76335-4
10. van der Wijk AE, Georgakopoulou T, Majolée J, van Bezu JSM, van der Stoel MM, van het Hof BJ et al. Microembolus clearance through angiophagy is an auxiliary mechanism preserving tissue perfusion in the rat brain. Acta neuropathologica communications. 2020 Dec;8(1). 195. https://doi.org/10.1186/s40478-020-01071-9
11. Kraal T, Lübbers J, van den Bekerom MPJ, Alessie J, van Kooyk Y, Eygendaal D et al. The puzzling pathophysiology of frozen shoulders - a scoping review. International Orthopaedics. 2020 Dec;7(1):91. 91. https://doi.org/10.1186/s40634-020-00307-w
12. Nijen Twilhaar MK, Czentner Colomo L, Grabowska J, Affandi AJ, Olesek K, Lau J et al. Optimization of Liposomes for Antigen Targeting to Splenic CD169+ Macrophages. International journal of pharmaceutics. 2020 Nov 25;12(12). https://doi.org/10.3390/pharmaceutics12121138
13. Duru G, Heemskerk N, van Egmond M. A Window of Opportunity: Targeting Cancer Endothelium to Enhance Immunotherapy. Frontiers in Immunology. 2020 Nov 11;11. 584723. https://doi.org/doi:10.3389/fimmu.2020.584723
14. Van den Bossche J. Fatty exosomes hamper antitumor immunity. Science Translational Medicine. 2020 Nov 11;12(569). eabf4685. https://doi.org/10.1126/scitranslmed.abf4685
15. Dammeijer F, van Gulijk M, Mulder EE, Lukkes M, Klaase L, van den Bosch T et al. The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes. Cancer Cell. 2020 Nov 9;38(5):685-700.e8. https://doi.org/10.1016/j.ccell.2020.09.001
16. de Goede KE, Driessen AJM, Van den Bossche J. Metabolic Cancer-Macrophage Crosstalk in the Tumor Microenvironment. Biology. 2020 Nov 7;9(11):1-17. 380. https://doi.org/10.3390/biology9110380
17. Artyomov MN, Van den Bossche J. Immunometabolism in the Single-Cell Era. Cell Metabolism. 2020 Nov 3;32(5):710-725. https://doi.org/10.1016/j.cmet.2020.09.013
18. Affandi AJ, Grabowska J, Olesek K, Lopez Venegas M, Barbaria A, Rodríguez E et al. Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes. Proceedings of the National Academy of Sciences of the United States of America. 2020 Nov 3;117(44):27528-27539. https://doi.org/10.1073/pnas.2006186117
19. Koetzier SC, van Langelaar J, Blok KM, van den Bosch TPP, Wierenga-Wolf AF, Melief M-J et al. Brain-homing CD4+ T cells display glucocorticoid-resistant features in MS. Neurology neuroimmunology & neuroinflammation. 2020 Nov 1;7(6). https://doi.org/10.1212/NXI.0000000000000894
20. Shang L, Deng D, Roffel S, Gibbs S. Differential influence of Streptococcus mitis on host response to metals in reconstructed human skin and oral mucosa. Contact Dermatitis. 2020 Nov 1;83(5):347-360. https://doi.org/10.1111/cod.13668, https://doi.org/10.1111/cod.13668
21. Michielon E, López González M, Burm JLA, Waaijman T, Jordanova ES, de Gruijl TD et al. Micro-environmental cross-talk in an organotypic human melanoma-in-skin model directs M2-like monocyte differentiation via IL-10. Cancer Immunology, Immunotherapy. 2020 Nov 1;69(11):2319-2331. https://doi.org/10.1007/s00262-020-02626-4
22. Rodrigues Neves CT, Spiekstra SW, de Graaf NPJ, Rustemeyer T, Feilzer AJ, Kleverlaan CJ et al. Titanium salts tested in reconstructed human skin with integrated MUTZ-3-derived Langerhans cells show an irritant rather than a sensitizing potential. Contact Dermatitis. 2020 Nov 1;83(5):337-346. https://doi.org/10.1111/cod.13666, https://doi.org/10.1111/cod.13666
23. Reintjens NRM, Tondini E, de Jong AR, Meeuwenoord NJ, Chiodo F, Peterse E et al. Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides. Journal of Medicinal Chemistry. 2020 Oct 22;63(20):11691-11706. https://doi.org/10.1021/acs.jmedchem.0c00851
24. Di Lorenzo F, Pither MD, Martufi M, Scarinci I, Guzmán-Caldentey J, Łakomiec E et al. Pairing bacteroides vulgatus LPS structure with its immunomodulatory effects on human cellular models. ACS Central Science. 2020 Sep 23;6(9):1602-1616. https://doi.org/10.1021/acscentsci.0c00791
25. Hoober JK, van Vliet SJ, Dudziak D, Eggink LL. Editorial: Sentinel CLECs at Immunological Decision Nodes. Frontiers in Immunology. 2020 Sep 10;11. 2066. https://doi.org/10.3389/fimmu.2020.02066
26. Blanas A, Zaal A, van der Haar Àvila I, Kempers M, Kruijssen L, de Kok M et al. FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State. Cancers. 2020 Sep 10;12(9):1-26. 2580. https://doi.org/10.3390/cancers12092580
27. Schetters STT, Kruijssen LJW, Crommentuijn MHW, Kalay H, den Haan JMM, van Kooyk Y. Immunological dynamics after subcutaneous immunization with a squalene-based oil-in-water adjuvant. FASEB Journal. 2020 Sep 1;34(9):12406-12418. https://doi.org/10.1096/fj.202000848R
28. Vila Cuenca M, Hordijk PL, Vervloet MG. Most exposed: the endothelium in chronic kidney disease. Nephrology, Dialysis, Transplantation. 2020 Sep 1;35(9):1478-1487. gfz055. https://doi.org/10.1093/ndt/gfz055, https://doi.org/10.1093/ndt/gfz055
29. Meijers AS, Troost R, Ummels R, Maaskant J, Speer A, Nejentsev S et al. Efficient genome editing in pathogenic mycobacteria using Streptococcus thermophilus CRISPR1-Cas9. Tuberculosis. 2020 Sep;124. 101983. https://doi.org/10.1016/j.tube.2020.101983
30. Van den Bossche J. Metabolic control of NLRP3 inflammasome by itaconation. Science Translational Medicine. 2020 Sep. https://doi.org/10.1126/scitranslmed.abe1714
31. Harber KJ, de Goede KE, Verberk SGS, Meinster E, de Vries HE, van Weeghel M et al. Succinate is an inflammation-induced immunoregulatory metabolite in macrophages. Metabolites. 2020 Sep;10(9):1-14. 372. https://doi.org/10.3390/metabo10090372
32. Kwesi-Maliepaard EM, Aslam MA, Alemdehy MF, Van Den Brand TV, McLean C, Vlaming H et al. The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 2020 Aug 25;117(34):20706-20716. https://doi.org/10.1073/pnas.1920372117
33. BtRAIN Network. Advancing brain barriers RNA sequencing: Guidelines from experimental design to publication. FLUIDS AND BARRIERS OF THE CNS. 2020 Aug 18;17(1). 51. https://doi.org/10.1186/s12987-020-00207-2
34. Cornelissen LAM, Blanas A, Zaal A, van der Horst JC, Kruijssen LJW, O’Toole T et al. Tn Antigen Expression Contributes to an Immune Suppressive Microenvironment and Drives Tumor Growth in Colorectal Cancer. Frontiers in Oncology. 2020 Aug 18;10. 1622. https://doi.org/10.3389/fonc.2020.01622
35. Dickhoff C, Senan S, Schneiders FL, Veltman J, Hashemi S, Daniels JMA et al. Ipilimumab plus nivolumab and chemoradiotherapy followed by surgery in patients with resectable and borderline resectable T3-4N0-1 non-small cell lung cancer: The INCREASE trial. BMC Cancer. 2020 Aug 14;20(1). 764. https://doi.org/10.1186/s12885-020-07263-9
36. Hähnlein JS, Nadafi R, de Jong TA, Semmelink JF, Remmerswaal EBM, Safy M et al. Human lymph node stromal cells have the machinery to regulate peripheral tolerance during health and rheumatoid arthritis. International Journal of Molecular Sciences. 2020 Aug 2;21(16):1-20. 5713. https://doi.org/10.3390/ijms21165713
37. Pirro M, Mohammed Y, van Vliet SJ, Rombouts Y, Sciacca A, de Ru AH et al. N-glycoproteins have a major role in mgl binding to colorectal cancer cell lines: Associations with overall proteome diversity. International Journal of Molecular Sciences. 2020 Aug 1;21(15):1-13. 5522. https://doi.org/10.3390/ijms21155522
38. Kooij G, Derada Troletti C, Leuti A, Norris PC, Riley I, Albanese M et al. Specialized differentially pro-resolving altered in peripheral lipid mediators blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction. Haematologica. 2020 Aug 1;105(8):2056-2070. https://doi.org/10.3324/haematol.2019.219519
39. BIA Study Group. Alterations of Gut Microbiota and the Brain-Immune-Intestine Axis in Patients With Relapsing-Remitting Multiple Sclerosis After Treatment With Oral Cladribine: Protocol for a Prospective Observational Study. JMIR Research Protocols. 2020 Jul 29;9(7). e16162. https://doi.org/10.2196/16162
40. Helderman RFCPA, Löke DR, Verhoeff J, Rodermond HM, van Bochove GGW, Boon M et al. The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines. Cells. 2020 Jul 25;9(8). https://doi.org/10.3390/cells9081775
41. Schetters STT, Rodriguez E, Kruijssen LJW, Crommentuijn MHW, Boon L, Van Den Bossche J et al. Monocyte-derived APCs are central to the response of PD1 checkpoint blockade and provide a therapeutic target for combination therapy. Journal for Immunotherapy of Cancer. 2020 Jul 19;8(2). 2020000588. https://doi.org/10.1136/jitc-2020-000588
42. van der Leeden B. Early diagnosis is associated with improved clinical outcomes in benign esophageal perforation: an individual patient data meta-analysis. Surgical Endoscopy. 2020 Jul 17. https://doi.org/10.1007/s00464-020-07806-y
43. Li RJE, Hogervorst TP, Achilli S, Bruijns SCM, Spiekstra S, Vivès C et al. Targeting of the C-Type Lectin Receptor Langerin Using Bifunctional Mannosylated Antigens. Frontiers in Cell and Developmental Biology. 2020 Jul 14;8. 556. https://doi.org/10.3389/fcell.2020.00556
44. Schouten M, Bielefeld P, Garcia-Corzo L, Passchier EMJ, Gradari S, Jungenitz T et al. Circadian glucocorticoid oscillations preserve a population of adult hippocampal neural stem cells in the aging brain. Molecular Psychiatry. 2020 Jul 1;25(7):1382-1405. https://doi.org/10.1038/s41380-019-0440-2
45. Forgione RE, Di Carluccio C, Guzmán-Caldentey J, Gaglione R, Battista F, Chiodo F et al. Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10. iScience. 2020 Jun 26;23(6). 101231. https://doi.org/10.1016/j.isci.2020.101231
46. Van den Bossche J. Improving metabolic fitness of antitumor immune cells. Science Translational Medicine. 2020 Jun 17;12(548). eabc8947. https://doi.org/10.1126/scitranslmed.abc8947
47. Zhang T, van Die I, Tefsen B, van Vliet SJ, Laan LC, Zhang J et al. Differential O- and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior. Frontiers in Oncology. 2020 Jun 2;10. 732. https://doi.org/10.3389/fonc.2020.00732
48. de Graaf NPJ, Bontkes HJ, Roffel S, Kleverlaan CJ, Rustemeyer T, Gibbs S et al. Non–heat inactivated autologous serum increases accuracy of in vitro CFSE lymphocyte proliferation test (LPT) for nickel. Clinical and Experimental Allergy. 2020 Jun 1;50(6):722-732. https://doi.org/10.1111/cea.13603
49. Vahav I, van den Broek LJ, Thon M, Monsuur HN, Spiekstra SW, Atac B et al. Reconstructed human skin shows epidermal invagination towards integrated neopapillae indicating early hair follicle formation in vitro. Journal of Tissue Engineering and Regenerative Medicine. 2020 Jun 1;14(6):761-773. https://doi.org/10.1002/term.3039
50. van Delft MAM, Huizinga TWJ. An overview of autoantibodies in rheumatoid arthritis. Journal of Autoimmunity. 2020 Jun;110. 102392. https://doi.org/10.1016/j.jaut.2019.102392
51. Koning JJ, Mebius RE. Stromal cells and immune cells involved in formation of lymph nodes and their niches. Current Opinion in Immunology. 2020 Jun;64:20-25. https://doi.org/10.1016/j.coi.2020.03.003
52. Van den Bossche J. A brake on inflammaging. Science Translational Medicine. 2020 May 27;12(545). eabb7104. https://doi.org/10.1126/scitranslmed.abb7104
53. Stolk DA, de Haas A, Vree J, Duinkerken S, Lübbers J, van de Ven R et al. Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T- and iNKT Cell Responses. Frontiers in Immunology. 2020 May 27;11. 990. https://doi.org/10.3389/fimmu.2020.00990
54. Limandjaja GC, Niessen FB, Scheper RJ, Gibbs S. The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models. Frontiers in Cell and Developmental Biology. 2020 May 26;8. 360. https://doi.org/10.3389/fcell.2020.00360
55. Chiodo F. Novel ACE2-Independent Carbohydrate-Binding of SARS-CoV-2 Spike Protein to Host Lectins and Lung Microbiota. Biorxiv. 2020 May 14. https://doi.org/10.1101/2020.05.13.092478
56. van Haasterecht L, Zada L, Schmidt RW, de Bakker E, Barbé E, Leslie HA et al. Label-free Stimulated Raman Scattering imaging reveals silicone breast implant material in tissue. Journal of biophotonics. 2020 May 1;13(5):e201960197. e201960197. https://doi.org/10.1002/jbio.201960197
57.Qin T, Prins S, Groeneveld GJ, Van Westen G, de Vries HE, Wong YC et al. Utility of Animal Models to Understand Human Alzheimer's Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals. International Journal of Molecular Sciences. 2020 May 1;21(9). 3158. https://doi.org/10.3390/ijms21093158
58.van Olst L, Verhaege D, Franssen M, Kamermans A, Roucourt B, Carmans S et al. Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model. Neurobiology of Aging. 2020 May;89:89-98. https://doi.org/10.1016/j.neurobiolaging.2020.01.003
59.Papapietro O, Chandra A, Eletto D, Inglott S, Plagnol V, Curtis J et al. Topoisomerase 2β mutation impairs early B-cell development. Blood. 2020 Apr 23;135(17):1497-1501. https://doi.org/10.1182/BLOOD.2019003299
60.Crommentuijn MHW, Schetters STT, Dusoswa SA, Kruijssen LJW, Garcia-Vallejo JJ, van Kooyk Y. Immune involvement of the contralateral hemisphere in a glioblastoma mouse model. Journal for Immunotherapy of Cancer. 2020 Apr 16;8(1). e000323. https://doi.org/10.1136/jitc-2019-000323
61.Melo CVBD, Hermida MDER, Mesquita BR, Fontes JLM, Koning JJ, Solcà MDS et al. Phenotypical Characterization of Spleen Remodeling in Murine Experimental Visceral Leishmaniasis. Frontiers in Immunology. 2020 Apr 15;11. 653. https://doi.org/10.3389/fimmu.2020.00653
62.Schetters STT, Jong WSP, Kruijssen LJW, Saparoea HBVDBV, Engels S, Unger WWJ et al. Bacterial inclusion bodies function as vehicles for dendritic cell-mediated T cell responses. CELLULAR & MOLECULAR IMMUNOLOGY. 2020 Apr 1;17(4):415-417. https://doi.org/10.1038/s41423-019-0298-x
63.Limandjaja GC, Belien JM, Scheper RJ, Niessen FB, Gibbs S. Hypertrophic and keloid scars fail to progress from the CD34−/α-smooth muscle actin (α-SMA)+ immature scar phenotype and show gradient differences in α-SMA and p16 expression. British Journal of Dermatology. 2020 Apr 1;182(4):974-986. https://doi.org/10.1111/bjd.18219
64.Van den Bossche J. Macrophages make you stronger. Science Translational Medicine. 2020 Apr 1;12(537). eabb5665. https://doi.org/10.1126/scitranslmed.abb5665
65.Turaihi AH, Serné EH, Molthoff CFM, Koning JJ, Knol J, Niessen HW et al. Perivascular Adipose Tissue Controls Insulin-Stimulated Perfusion, Mitochondrial Protein Expression and Glucose Uptake in Muscle Through Adipomuscular Arterioles. Diabetes. 2020 Apr 1;69(4):603-613. https://doi.org/10.2337/db18-1066
66.Schulte R, Wohlleber D, Unrau L, Geers B, Metzger C, Erhardt A et al. Pioglitazone-mediated peroxisome proliferator-activated receptor γ activation aggravates murine immune-mediated hepatitis. International Journal of Molecular Sciences. 2020 Apr 1;21(7). 2523. https://doi.org/10.3390/ijms21072523
67.Kastelein AW, Vos LMC, van Baal JOAM, Koning JJ, Hira VVV, Nieuwland R et al. Poor perfusion of the microvasculature in peritoneal metastases of ovarian cancer. Clinical and Experimental Metastasis. 2020 Apr 1;37(2):293-304. https://doi.org/10.1007/s10585-020-10024-4
68.Pirro M, Rombouts Y, Stella A, Neyrolles O, Burlet-Schiltz O, van Vliet SJ et al. Characterization of Macrophage Galactose-type Lectin (MGL) Ligands in Colorectal Cancer Cell Lines. Biochimica et Biophysica Acta (BBA) - General Subjects. 2020 Apr;1864(4). 129513. https://doi.org/10.1016/j.bbagen.2020.129513
69.Erkelens MN, Goverse G, Konijn T, Molenaar R, Beijer MR, Van den Bossche J et al. Intestinal Macrophages Balance Inflammatory Expression Profiles via Vitamin A and Dectin-1-Mediated Signaling. Frontiers in Immunology. 2020 Mar 31;11. 551. https://doi.org/10.3389/fimmu.2020.00551
70.Nadafi R, Gago de Graça C, Keuning ED, Koning JJ, de Kivit S, Konijn T et al. Lymph Node Stromal Cells Generate Antigen-Specific Regulatory T Cells and Control Autoreactive T and B Cell Responses. Cell Reports. 2020 Mar 24;30(12):4110-4123.e4. https://doi.org/10.1016/j.celrep.2020.03.007
71.Hogervorst TP, Li RJE, Marino L, Bruijns SCM, Meeuwenoord NJ, Filippov DV et al. C-mannosyl lysine for solid phase assembly of mannosylated peptide conjugate cancer vaccines. Acs chemical biology. 2020 Mar 20;15(3):728-739. https://doi.org/10.1021/acschembio.9b00987
72. Rodríguez-Lorenzo S, Ferreira Francisco DM, Vos R, Van Het Hof B, Rijnsburger M, Schroten H et al. Altered secretory and neuroprotective function of the choroid plexus in progressive multiple sclerosis. Acta neuropathologica communications. 2020 Mar 19;8(1). 35. https://doi.org/10.1186/s40478-020-00903-y
73. Houben E, Janssens K, Hermans D, Vandooren J, van den Haute C, Schepers M et al. Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination. Proceedings of the National Academy of Sciences of the United States of America. 2020 Mar 3;117(9):5028-5038. https://doi.org/10.1073/pnas.1912910117
74. Silva Z, Ferro T, Almeida D, Soares H, Ferreira JA, Deschepper FM et al. MHC class I stability is modulated by cell surface sialylation in human dendritic cells. Pharmaceutics. 2020 Mar;12(3). 249. https://doi.org/10.3390/pharmaceutics12030249
75. Boon BDC, Bulk M, Jonker AJ, Morrema THJ, van den Berg E, Popovic M et al. The coarse-grained A beta plaque; a 'new' kid on the block in early-onset Alzheimer's disease, showing a strong association with both inflammatory and vascular changes. Neuropathology and Applied Neurobiology. 2020 Mar;46:39-40. https://doi.org/10.1007/s00401-020-02198-8
76. Rodríguez-Lorenzo S, Konings J, Van Der Pol S, Kamermans A, Amor S, Van Horssen J et al. Erratum: Inflammation of the choroid plexus in progressive multiple sclerosis: Accumulation of granulocytes and T cells (Acta Neuropathologica Communications (2020) 8 (9) DOI: 10.1186/s40478-020-0885-1). Acta neuropathologica communications. 2020 Feb 26;8(1). 24. https://doi.org/10.1186/s40478-020-00899-5
77. Zaal A, Li RJE, Lübbers J, Bruijns SCM, Kalay H, van Kooyk Y et al. Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells. Frontiers in Immunology. 2020 Feb 25;11. 305. https://doi.org/10.3389/fimmu.2020.00305
78. Mehra A, Guérit S, Macrez R, Gosselet F, Sevin E, Lebas H et al. Nonionotropic Action of Endothelial NMDA Receptors on Blood-Brain Barrier Permeability via Rho/ROCK-Mediated Phosphorylation of Myosin. Journal of Neuroscience. 2020 Feb 19;40(8):1778-1787. https://doi.org/10.1523/JNEUROSCI.0969-19.2019
79. Dusoswa SA, Verhoeff J, Abels E, Méndez-Huergo SP, Croci DO, Kuijper LH et al. Glioblastomas exploit truncated O-linked glycans for local and distant immune modulation via the macrophage galactose-type lectin. Proceedings of the National Academy of Sciences of the United States of America. 2020 Feb 18;117(7):3693-3703. https://doi.org/10.1073/pnas.1907921117
80. Zwiers A, van Wanrooij RLJ, Dieckman T, Nijeboer P, Kraal G, Bouma G. Celiac disease associated SNP rs17810546 is located in a gene silencing region. Gene. 2020 Feb 5;726. 144165. https://doi.org/10.1016/j.gene.2019.144165
81. Rodríguez-Lorenzo S, Konings J, Van Der Pol S, Kamermans A, Amor S, Van Horssen J et al. Inflammation of the choroid plexus in progressive multiple sclerosis: Accumulation of granulocytes and T cells. Acta neuropathologica communications. 2020 Feb 3;8(1). 9. https://doi.org/10.1186/s40478-020-0885-1
82. Broekaart DWM, van Scheppingen J, Anink JJ, Wierts L, van het Hof B, Jansen FE et al. Increased matrix metalloproteinases expression in tuberous sclerosis complex: modulation by microRNA 146a and 147b in vitro. Neuropathology and Applied Neurobiology. 2020 Feb 1;46(2):142-159. https://doi.org/10.1111/nan.12572
83. Hagens MHJ, Golla SSV, Janssen B, Vugts DJ, Beaino W, Windhorst AD et al. The P2X7 receptor tracer [11C]SMW139 as an in vivo marker of neuroinflammation in multiple sclerosis: a first-in man study. European Journal of Nuclear Medicine and Molecular Imaging. 2020 Feb 1;47(2):379-389. https://doi.org/10.1007/s00259-019-04550-x
84. Wolde M, Laan LC, Medhin G, Gadissa E, Berhe N, Tsegaye A. Human monocytes/macrophage inflammatory cytokine changes following in vivo and in vitro Schistomam manoni infection. Journal of Inflammation Research. 2020 Jan 1;13:35-43. https://doi.org/10.2147/JIR.S233381
85. Bikhezar F, de Kruijff RM, van der Meer AJGM, Torrelo Villa G, van der Pol SMA, Becerril Aragon G et al. Preclinical evaluation of binimetinib (MEK162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma. Journal of Neuro-Oncology. 2020 Jan 1;146(2):239-246. https://doi.org/10.1007/s11060-019-03365-y
86. Bogie JFJ, Haidar M, Kooij G, Hendriks JJA. Fatty acid metabolism in the progression and resolution of CNS disorders. Advanced Drug Delivery Reviews. 2020 Jan;159:198-213. https://doi.org/10.1016/j.addr.2020.01.004
87. Crivelli SM, Giovagnoni C, Visseren L, Scheithauer A-L, de Wit N, den Hoedt S et al. Sphingolipids in Alzheimer's disease, how can we target them? Advanced Drug Delivery Reviews. 2020 Jan;159:214-231. https://doi.org/10.1016/j.addr.2019.12.003