Publications 2017

1. Troletti CD, Lopes Pinheiro MA, Charabati M, Gowing E, van Het Hof B, der Pol SMAV, Geerts D, Prat A, Fontijn RD, Unger WW, de Vries HE. Notch signaling isimpaired during inflammation in a Lunatic Fringe-dependent manner. Brain Behav Immun. 2017 Dec 28. pii: S0889-1591(17)30557-3. doi: 10.1016/j.bbi.2017.12.016. [Epub ahead of print] PubMed PMID: 29289661.

2. Beaino W, Janssen B, Kooij G, van der Pol SMA, van Het Hof B, van Horssen J, Windhorst AD, de Vries HE. Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis. J Neuroinflammation. 2017 Dec 22;14(1):259. doi: 10.1186/s12974-017-1034-z. PubMed PMID: 29273052; PubMed Central PMCID: PMC5741931.

3. Heineke MH, Ballering AV, Jamin A, Ben Mkaddem S, Monteiro RC, Van Egmond M. New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Schönlein purpura). Autoimmun Rev. 2017 Dec;16(12):1246-1253. doi:10.1016/j.autrev.2017.10.009. Epub 2017 Oct 14. Review. PubMed PMID: 29037908.

4. Holst S, Belo AI, Giovannetti E, van Die I, Wuhrer M. Profiling of different pancreatic cancer cells used as models for metastatic behaviour shows large variation in their N-glycosylation. Sci Rep. 2017 Nov 30;7(1):16623. doi:
10.1038/s41598-017-16811-6. PubMed PMID: 29192278.

5. Van Die I, Cummings RD. The Mannose Receptor in Regulation of Helminth-mediated Host Immunity.  Front Immunol. 2017 Nov 29;8:1677. doi: 10.3389/fimmu.2017.01677. eCollection 2017. Review. PMID: 29238348

6. Habbeddine M, Verthuy C, Rastoin O, Chasson L, Bebien M, Bajenoff M, Adriouch  S, den Haan JMM, Penninger JM, Lawrence T. Receptor Activator of NF- κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone. Cell Rep. 2017 Nov 28;21(9):2515-2527. doi: 10.1016/j.celrep.2017.10.111. PubMed PMID: 29186688.

7. Li RE, van Vliet SJ, van Kooyk Y. Using the glycan toolbox for pathogenic interventions and glycan immunotherapy. Curr Opin Biotechnol. 2017 Nov 22;51:24-31. doi: 10.1016/j.copbio.2017.11.003. [Epub ahead of print] Review.PubMed PMID: 29175707.

8. Meinderts SM, Sins JWR, Fijnvandraat K, Nagelkerke SQ, Geissler J, Tanck MW, Bruggeman C, Biemond BJ, Rijneveld AW, Kerkhoffs JH, Pakdaman S, Habibi A, van Bruggen R, Kuijpers TW, Pirenne F, van den Berg TK. Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease. Blood. 2017 Nov 9;130(19):2121-2130. doi: 10.1182/blood-2017-05-784876. Epub 2017 Sep 12. PubMed PMID: 28899854. These authors contributed equally

9. Midttun HLE, Acevedo N, Skallerup P, Almeida S, Skovgaard K, Andresen L, Skov  S, Caraballo L, van Die I, Jørgensen CB, Fredholm M, Thamsborg SM, Nejsum P, Williams AR. Ascaris suum infection down-regulates inflammatory pathways in the pig intestine in vivo and in human dendritic cells in vitro. J Infect Dis. 2017 Nov 9. doi: 10.1093/infdis/jix585. [Epub ahead of print] PubMed PMID: 29136163.

10. Wolde M, Berhe N, van Die I, Medhin G, Tsegaye A. Knowledge and practice on prevention of diabetes mellitus among Diabetes mellitus family members, in suburban cities in Ethiopia. BMC Res Notes. 2017 Nov 2;10(1):551. doi: 10.1186/s13104-017-2871-7. PubMed PMID: 29096704; PubMed Central PMCID: PMC5669018.

11. Lagerweij T, Dusoswa SA, Negrean A, Hendrikx EML, de Vries HE, Kole J, Garcia-Vallejo JJ, Mansvelder HD, Vandertop WP, Noske DP, Tannous BA, Musters RJP, van Kooyk Y, Wesseling P, Zhao XW, Wurdinger T. Optical clearing and fluorescence deep-tissue imaging for 3D quantitative analysis of the brain tumor microenvironment. Angiogenesis. 2017 Nov;20(4):533-546. doi: 10.1007/s10456-017-9565-6. Epub 2017 Jul 11. PubMed PMID: 28699046; PubMed Central PMCID: PMC5660146.

12. van der Spek AH, Surovtseva OV, Aan S, Tool ATJ, van de Geer A, Demir K, van Gucht ALM, van Trotsenburg ASP, van den Berg TK, Fliers E, Boelen A. Increased circulating interleukin-8 in patients with resistance to thyroid hormone receptor α . Endocr Connect. 2017 Nov;6(8):731-740. doi: 10.1530/EC-17-0213. PubMed PMID: 29101248; PubMed Central PMCID: PMC5670275.

13. Malinova TS, Dijkstra CD, de Vries HE. Serotonin: A mediator of the gut-brain axis in multiple sclerosis. Mult Scler. 2017 Nov 1:1352458517739975. doi: 10.1177/1352458517739975. [Epub ahead of print] PubMed PMID: 29117778.

14. de Wit NM, Vanmol J, Kamermans A, Hendriks J, de Vries HE. Inflammation at the blood-brain barrier: The role of liver X receptors. Neurobiol Dis. 2017 Nov;107:57-65. doi: 10.1016/j.nbd.2016.09.015. Epub 2016 Sep 20. Review. PubMed PMID: 27659108.

15. Bar-Ephraim YE, Cornelissen F, Papazian N, Konijn T, Hoogenboezem RM, Sanders MA, Westerman BA, Gönültas M, Kwekkeboom J, Den Haan JMM, Reijmers RM, Mebius RE, Cupedo T. Cross-Tissue Transcriptomic Analysis of Human Secondary Lymphoid Organ-Residing ILC3s Reveals a Quiescent State in the Absence of Inflammation. Cell Rep. 2017 Oct 17;21(3):823-833. doi: 10.1016/j.celrep.2017.09.070. PubMed PMID: 29045847.

16. Heineke MH, van der Steen LPE, Korthouwer RM, Hage JJ, Langedijk JPM, Benschop JJ, Bakema JE, Slootstra JW, van Egmond M. Peptide mimetics of immunoglobulin A (IgA) and Fc αRI block IgA-induced human neutrophil activation and migration. Eur J Immunol. 2017 Oct;47(10):1835-1845. doi:10.1002/eji.201646782. Epub 2017 Sep 6. PubMed PMID: 28736835; PubMed Central PMCID: PMC5659136.

17. de Boer M, van Leeuwen K, Geissler J, van Alphen F, de Vries E, van der Kuip M, Terheggen SWJ, Janssen H, van den Berg TK, Meijer AB, Roos D, Kuijpers TW. Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils. Hum Mutat. 2017 Oct;38(10):1402-1411. doi: 10.1002/humu.23271. Epub 2017 Jun 15. PubMed PMID: 28585318.

18. van Dinther D, Stolk DA, van de Ven R, van Kooyk Y, de Gruijl TD, den Haan JMM. Targeting C-type lectin receptors: a high-carbohydrate diet for dendritic cells to improve cancer vaccines. J Leukoc Biol. 2017 Oct;102(4):1017-1034. doi: 10.1189/jlb.5MR0217-059RR. Epub 2017 Jul 20. Review. PubMed PMID: 28729358; PubMed Central PMCID: PMC5597514.

19. Breedveld A, Groot Kormelink T, van Egmond M, de Jong EC. Granulocytes as modulators of dendritic cell function. J Leukoc Biol. 2017 Oct;102(4):1003-1016. doi: 10.1189/jlb.4MR0217-048RR. Epub 2017 Jun 22. Review. PubMed PMID: 28642280.

20. van den Berg SM, van Dam AD, Kusters PJH, Beckers L, den Toom M, van der Velden S, Van den Bossche J, van Die I, Boon MR, Rensen PCN, Lutgens E, de Winther MPJ. Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils. J Mol Endocrinol. 2017 Oct;59(3):245-255. doi: 10.1530/JME-17-0112. Epub 2017 Jul 10. PubMed PMID: 28694301.

21. Treffers LW, Zhao XW, van der Heijden J, Nagelkerke SQ, van Rees DJ, Gonzalez P, Geissler J, Verkuijlen P, van Houdt M, de Boer M, Kuijpers TW, van den Berg TK, Matlung HL. Genetic variation of human neutrophil Fc γ receptors and SIRP α in antibody-dependent cellular cytotoxicity towards cancer cells. Eur J Immunol. 2017 Sep 27. doi: 10.1002/eji.201747215. [Epub ahead of print] PubMed PMID: 28952147. These authors contributed equally.

22. Machado Y, Duinkerken S, Hoepflinger V, Mayr M, Korotchenko E, Kurtaj A, Pablos I, Steiner M, Stoecklinger A, Lübbers J, Schmid M, Ritter U, Scheiblhofer S, Ablinger M, Wally V, Hochmann S, Raninger AM, Strunk D, van Kooyk Y, Thalhamer J, Weiss R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. J Control Release. 2017 Sep 14;266:87-99. doi: 0.1016/j.jconrel.2017.09.020. [Epub ahead of print] PubMed PMID: 28919557.

23. Lepka K, Volbracht K, Bill E, Schneider R, Rios N, Hildebrandt T, Ingwersen J, Prozorovski T, Lillig CH, van Horssen J, Steinman L, Hartung HP, Radi R, Holmgren A, Aktas O, Berndt C. Iron-sulfur glutaredoxin 2 protects
oligodendrocytes against damage induced by nitric oxide release from activated microglia. Glia. 2017 Sep;65(9):1521-1534. doi: 10.1002/glia.23178. Epub 2017 Jun 15. PubMed PMID: 28618115.

24. Dekkers G, Treffers L, Plomp R, Bentlage AEH, de Boer M, Koeleman CAM, Lissenberg-Thunnissen SN, Visser R, Brouwer M, Mok JY, Matlung H, van den Berg TK, van Esch WJE, Kuijpers TW, Wouters D, Rispens T, Wuhrer M, Vidarsson G. Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities. Front Immunol. 2017 Aug 2;8:877. doi: 10.3389/fimmu.2017.00877. eCollection 2017. PubMed PMID: 28824618; PubMed Central PMCID: PMC5539844.

25. Haeberlein S, Obieglo K, Ozir-Fazalalikhan A, Chayé MAM, Veninga H, van der Vlugt LEPM, Voskamp A, Boon L, den Haan JMM, Westerhof LB, Wilbers RHP, Schots A, Schramm G, Hokke CH, Smits HH. Schistosome egg antigens, including the glycoprotein IPSE/alpha-1, trigger the development of regulatory B cells. PLoS Pathog. 2017 Jul 28;13(7):e1006539. doi: 10.1371/journal.ppat.1006539. eCollection 2017 Jul. PubMed PMID: 28753651; PubMed Central PMCID: PMC5550006.

26. 't Hart BA, Dunham J, Faber BW, Laman JD, van Horssen J, Bauer J, Kap YS. A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model. Front Immunol. 2017 Jul 11;8:804. doi: 10.3389/fimmu.2017.00804. eCollection 2017. Review. PubMed PMID: 28744286; PubMed Central PMCID: PMC5504154.

27. Kuijpers TW, Tool ATJ, van der Bijl I, de Boer M, van Houdt M, de Cuyper IM, Roos D, van Alphen F, van Leeuwen K, Cambridge EL, Arends MJ, Dougan G, Clare S, Ramirez-Solis R, Pals ST, Adams DJ, Meijer AB, van den Berg TK. Combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency. J Allergy Clin Immunol. 2017 Jul;140(1):273-277.e10. doi:10.1016/j.jaci.2016.09.061. Epub 2016 Dec 10. PubMed PMID: 27965109.

28. Bruggeman CW, Dekkers G, Bentlage AEH, Treffers LW, Nagelkerke SQ, Lissenberg-Thunnissen S, Koeleman CAM, Wuhrer M, van den Berg TK, Rispens T, Vidarsson G, Kuijpers TW. Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fc γ Receptor Profile. J Immunol. 2017 Jul 1;199(1):204-211. doi: 10.4049/jimmunol.1700116. Epub 2017 May 31. PubMed PMID: 28566370.

29. van Horssen J, van Schaik P, Witte M. Inflammation and mitochondrial dysfunction: A vicious circle in neurodegenerative disorders? Neurosci Lett. 2017 Jun 28. pii: S0304-3940(17)30542-6. doi: 10.1016/j.neulet.2017.06.050. [Epub ahead of print] Review. PubMed PMID: 28668382.

30. Goverse G, Erkelens M, Mebius R. Response to Comment on "Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells". J Immunol. 2017 Jun 1;198(11):4188. doi: 10.4049/jimmunol.1700466. PubMed PMID: 28533279.

31. Dunham J, Bauer J, Campbell GR, Mahad DJ, van Driel N, van der Pol SMA, 't Hart BA, Lassmann H, Laman JD, van Horssen J, Kap YS. Oxidative Injury and Iron Redistribution Are Pathological Hallmarks of Marmoset Experimental Autoimmune Encephalomyelitis. J Neuropathol Exp Neurol. 2017 Jun 1;76(6):467-478. doi: 10.1093/jnen/nlx034. PubMed PMID: 28505283.

32. Bridel C, Koel-Simmelink MJA, Peferoen L, Derada Troletti C, Durieux S, Gorter R, Nutma E, Gami P, Iacobaeus E, Brundin L, Kuhle J, Vrenken H, Killestein J, Piersma SR, Pham TV, De Vries HE, Amor S, Jimenez CR, Teunissen CE. Brain endothelial cell expression of SPARCL-1 is specific to chronic multiple sclerosis lesions and is regulated by inflammatory mediators in vitro. Neuropathol Appl Neurobiol. 2017 May 24. doi: 10.1111/nan.12412. [Epub ahead of print] PubMed PMID: 28543098.

33. Braster R, Grewal S, Visser R, Einarsdottir HK, van Egmond M, Vidarsson G, Bögels M. Human IgG3 with extended half-life does not improve Fc-gamma receptor-mediated cancer antibody therapies in mice. PLoS One. 2017 May 19;12(5):e0177736. doi: 10.1371/journal.pone.0177736. eCollection 2017. PubMed PMID: 28542406; PubMed Central PMCID: PMC5438146.

34. Deddens LH, van Tilborg GAF, van der Marel K, Hunt H, van der Toorn A, Viergever MA, de Vries HE, Dijkhuizen RM. In Vivo Molecular MRI of ICAM-1 Expression on Endothelium and Leukocytes from Subacute to Chronic Stages After Experimental Stroke. Transl Stroke Res. 2017 May 16. doi: 10.1007/s12975-017-0536-4. [Epub ahead of print] PubMed PMID: 28509283; PubMed Central PMCID: PMC5590030.

35. Aarts SABM, Seijkens TTP, Kusters PJH, van der Pol SMA, Zarzycka B, Heijnen PDAM, Beckers L, den Toom M, Gijbels MJJ, Boon L, Weber C, de Vries HE, Nicolaes  GAF, Dijkstra CD, Kooij G, Lutgens E. Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation. J Neuroinflammation. 2017 May 12;14(1):105. doi: 10.1186/s12974-017-0875-9. PubMed PMID: 28494768; PubMed Central PMCID: PMC5427621.

36. Meinderts SM, Oldenborg PA, Beuger BM, Klei TRL, Johansson J, Kuijpers TW, Matozaki T, Huisman EJ, de Haas M, van den Berg TK*, van Bruggen R*. Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells. Blood Adv. 2017 May 26;1(14):875-886. doi: 10.1182/bloodadvances.2017004671. eCollection 2017 Jun 13. PubMed PMID: 29296731; PubMed Central PMCID: PMC5737592. These authors contributed equally

37. Yipp BG, Kim JH, Lima R, Zbytnuik LD, Petri B, Swanlund N, Ho M, Szeto VG, Tak T, Koenderman L, Pickkers P, Tool ATJ, Kuijpers TW, van den Berg TK, Looney MR, Krummel MF, Kubes P. The Lung is a Host Defense Niche for Immediate Neutrophil-Mediated Vascular Protection. Sci Immunol. 2017 Apr 28;2(10). pii: eaam8929. doi: 10.1126/sciimmunol.aam8929. PubMed PMID: 28626833; PubMed Central PMCID: PMC5472445.

38. Rodríguez E, Kalay H, Noya V, Brossard N, Giacomini C, van Kooyk Y, García-Vallejo JJ, Freire T. Fasciola hepatica glycoconjugates immuneregulate dendritic cells through the Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin inducing T cell anergy. Sci Rep. 2017 Apr 24;7:46748. doi: 10.1038/srep46748. PubMed PMID: 28436457; PubMed Central PMCID: PMC5402274.

39. Fehres CM, Duinkerken S, Bruijns SC, Kalay H, van Vliet SJ, Ambrosini M, de Gruijl TD, Unger WW, Garcia-Vallejo JJ, van Kooyk Y. Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells. Cell Mol Immunol. 2017 Apr;14(4):360-370. doi: 10.1038/cmi.2015.87. Epub 2015 Oct 12. PubMed PMID: 26456691; PubMed Central PMCID: PMC5380941.

40. Carvalho AN, Firuzi O, Gama MJ, Horssen JV, Saso L. Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope? Curr Drug Targets. 2017 Mar 30;18(6):705-718. doi:  10.2174/1389450117666160401120514. PubMed PMID: 27033198.

41. Cerutti C, Edwards LJ, de Vries HE, Sharrack B, Male DK, Romero IA. MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium. Sci Rep. 2017 Mar 30;7:45284. doi: 10.1038/srep45284. PubMed PMID: 28358058; PubMed Central PMCID: PMC5372244.

42. Rodríguez E, Carasi P, Frigerio S, da Costa V, van Vliet S, Noya V, Brossard N, van Kooyk Y, García-Vallejo JJ, Freire T. Fasciola hepatica Immune Regulates CD11c(+) Cells by Interacting with the Macrophage Gal/GalNAc Lectin. Front Immunol. 2017 Mar 15;8:264. doi: 10.3389/fimmu.2017.00264. eCollection 2017. PubMed PMID: 28360908; PubMed Central PMCID: PMC5350155.

43. Nossent AY, Bastiaansen AJ, Peters EA, de Vries MR, Aref Z, Welten SM, de Jager SC, van der Pouw Kraan TC, Quax PH. CCR7-CCL19/CCL21 Axis is Essential for Effective Arteriogenesis in a Murine Model of Hindlimb Ischemia. J Am Heart Assoc. 2017 Mar 8;6(3). pii: e005281. doi: 10.1161/JAHA.116.005281. PubMed PMID: 28275068; PubMed Central PMCID: PMC5524034.

44. Matlung HL, Szilagyi K, Barclay NA, van den Berg TK. The CD47-SIRP α signalling axis as an innate immune checkpoint in cancer. Immunol Rev. 2017 Mar;276(1):145-164. doi: 10.1111/imr.12527. Review. PubMed PMID: 28258703. These authors contributed equally

45. Williams AR, Klaver EJ, Laan LC, Ramsay A, Fryganas C, Difborg R, Kringel H, Reed JD, Mueller-Harvey I, Skov S, van Die I, Thamsborg SM. Co-operative suppression of inflammatory responses in human dendritic cells by plant proanthocyanidins and products from the parasitic nematode Trichuris suis. Immunology. 2017 Mar;150(3):312-328. doi: 10.1111/imm.12687. Epub 2016 Nov 30. PubMed PMID: 27905107; PubMed Central PMCID: PMC5290246.

46. Goverse G, Molenaar R, Macia L, Tan J, Erkelens MN, Konijn T, Knippenberg M, Cook EC, Hanekamp D, Veldhoen M, Hartog A, Roeselers G, Mackay CR, Mebius RE. Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells. J Immunol. 2017 Mar 1;198(5):2172-2181. doi: 10.4049/jimmunol.1600165. Epub 2017 Jan 18. PubMed PMID: 28100682.

47. Leurs CE, Podlesniy P, Trullas R, Balk L, Steenwijk MD, Malekzadeh A, Piehl. F, Uitdehaag BM, Killestein J, van Horssen J, Teunissen CE.Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment. Mult Scler. 2017 Mar 1:1352458517699874. doi: 10.1177/1352458517699874. [Epub ahead of print] PubMed PMID: 28294696.

48. Bogie JF, Boelen E, Louagie E, Delputte P, Elewaut D, van Horssen J, Hendriks. JJ, Hellings N. CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis. Mult Scler. 2017 Mar 1:1352458517698759. doi:
10.1177/1352458517698759. [Epub ahead of print] PubMed PMID: 28277099.

49. Hiemstra IH, van Hamme JL, Janssen MH, van den Berg TK, Kuijpers TW. Dexamethasone promotes granulocyte mobilization by prolonging the half-life of granulocyte-colony-stimulating factor in healthy donors for granulocyte transfusions. Transfusion. 2017 Mar;57(3):674-684. doi: 10.1111/trf.13941. Epub 2016 Dec 28. PubMed PMID: 28032635.

50. Erkelens MN, Mebius RE. Retinoic Acid and Immune Homeostasis: A Balancing Act. Trends Immunol. 2017 Mar;38(3):168-180. doi: 10.1016/j.it.2016.12.006. Epub 2017 Jan 13. Review. PubMed PMID: 28094101.

51. Bogie JF, Mailleux J, Wouters E, Jorissen W, Grajchen E, VanmolJ, Wouters K, Hellings N, Van Horsen J, Vanmierlo T, Hendriks. Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes. Sci Rep. 2017 Mar 20;7:44794. doi: 10.1038/srep44794. PMCID: PMC5357964 PMID: 28317919

52. Kuipers HF, Yoon J, van Horssen J, Han MH, Bollyky PL, Palmer TD, Steinman L. Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1745-E1754. doi:10.1073/pnas.1621314114. Epub 2017 Feb 14. PubMed PMID: 28196893; PubMed Central PMCID: PMC5338510.

53. Shikhagaie MM, Björklund ÅK, Mjösberg J, Erjefält JS, Cornelissen AS, Ros XR, Bal SM, Koning JJ, Mebius RE, Mori M, Bruchard M, Blom B, Spits H. Neuropilin-1Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates. Cell Rep. 2017 Feb 14;18(7):1761-1773. doi: 10.1016/j.celrep.2017.01.063. PubMed PMID: 28199847; PubMed Central PMCID: PMC5318658.

54. Klei TR, Meinderts SM, van den Berg TK, van Bruggen R. From the Cradle to the Grave: The Role of Macrophages in Erythropoiesis and Erythrophagocytosis. Front Immunol. 2017 Feb 2;8:73. doi: 10.3389/fimmu.2017.00073. eCollection 2017. Review. PubMed PMID: 28210260; PubMed Central PMCID: PMC5288342.

55. Nauta TD, van den Broek M, Gibbs S, van der Pouw-Kraan TC, Oudejans CB, van Hinsbergh VW, Koolwijk P. Identification of HIF-2 α-regulated genes that play a role in human microvascular endothelial sprouting during prolonged hypoxia in vitro. Angiogenesis. 2017 Feb;20(1):39-54. doi: 10.1007/s10456-016-9527-4. Epub 2016 Oct 3. PubMed PMID: 27699500; PubMed Central PMCID: PMC5306362.

56. Heineke MH, van Egmond M. Immunoglobulin A: magic bullet or Trojan horse? Eur J Clin Invest. 2017 Feb;47(2):184-192. doi: 10.1111/eci.12716. Epub 2017 Jan 19. Review. PubMed PMID: 28024097.

57. Laan LC, Williams AR, Stavenhagen K, Giera M, Kooij G, Vlasakov I, Kalay H, Kringel H, Nejsum P, Thamsborg SM, Wuhrer M, Dijkstra CD, Cummings RD, van Die I.The whipworm (Trichuris suis) secretes prostaglandin E2 to suppress proinflammatory properties in human dendritic cells. FASEB J. 2017 Feb;31(2):719-731. doi: 10.1096/fj.201600841R. Epub 2016 Nov 2. PubMed PMID: 27806992; PubMed Central PMCID: PMC5240662.

58. Mailleux J, Vanmierlo T, Bogie JF, Wouters E, Lütjohann D, Hendriks JJ, van Horssen J. Active liver X receptor signaling in phagocytes in multiple sclerosis lesions. Mult Scler. 2017 Feb 1:1352458517696595. doi: 10.1177/1352458517696595. [Epub ahead of print] PubMed PMID: 28273782.

59. Chakraborty A, de Wit NM, van der Flier WM, de Vries HE. The blood brain barrier in Alzheimer's disease. Vascul Pharmacol. 2017 Feb;89:12-18. doi:10.1016/j.vph.2016.11.008. Epub 2016 Nov 25. Review. PubMed PMID: 27894893.

60. van de Geer A, Gazendam RP, Tool AT, van Hamme JL, de Korte D, van den Berg TK, Zeerleder SS, Kuijpers TW. Characterization of buffy coat-derived granulocytes for clinical use: a comparison with granulocyte colony-stimulating factor/dexamethasone-pretreated donor-derived products. Vox Sang. 2017 Feb;112(2):173-182. doi: 10.1111/vox.12481. Epub 2017 Jan 25. PubMed PMID: 28120426.

61. Cummings RD, van Die I. Parasitic Infections. 2017. In: Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Darvill AG, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH, editors. Essentials of Glycobiology [Internet]. 3rd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2015-2017. Chapter 43. Available from http://www.ncbi.nlm.nih.gov/books/NBK453068/  PubMed PMID: 28876851.

62. Kekki H, Peltola M, van Vliet S, Bangma C, van Kooyk Y, Pettersson K. Improved cancer specificity in PSA assay using Aleuria aurantia lectin coated Eu-nanoparticles for detection. Clin Biochem. 2017 Jan;50(1-2):54-61.  doi:10.1016/j.clinbiochem.2016.06.015. Epub 2016 Nov 4. PubMed PMID: 27818346.

63. Braster R, Bögels M, Beelen RH, van Egmond M. The delicate balance of macrophages in colorectal cancer; their role in tumour development and therapeutic potential. Immunobiology. 2017 Jan;222(1):21-30. doi:
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64. Verbij FC, Sorvillo N, Kaijen PHP, Hrdinova J, Peyron I, Fijnheer R, Ten Brinke A, Meijer AB, van Alphen FPJ, van den Berg TK, Graversen JJH, Moestrup SK, Voorberg J. The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages. Blood Adv. 2017 Jan 16;1(5):293-305. doi: 10.1182/bloodadvances.2016001321. eCollection 2017 Jan 24. PubMed PMID: 29296945; PubMed Central PMCID: PMC5744037.

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